ProfJane Maguire

Professor Jane Maguire was awarded a PhD in Public Health and Medicine in 2010 from the University of Newcastle, Australia. She is the immediate outgoing Deputy Head of School (Research) in the School of Nursing and Midwifery. A registered nurse since 1983, Professor Maguire had 20 years’ clinical experience as a paediatric nurse before entering academia with a PhD examining  the influences of genetic variants on stroke risk and stroke outcome. Data from that PhD is still informing research generated by the International Stroke Genetics Consortium, an organisation which she has been an active steering committee member and past Chair, for over 12 years, with over 130 joint publications. Professor Maguire has been awarded over $3 million in grants and has an h-index of 38 and has published over 160 peer reviewed research papers in high impact journals, including Nature Genetics, Stroke, Neurology Genetics, and Radiology. She reviews articles for more than a dozen journals and 5 book Chapter publications. Professor Maguire has multiple global researcher partners in the USA, Europe, Asia and the UK.

Visible and Active International Research profile: 

Prof Maguire is a global leader in stroke genetics research through her ongoing role as tri-leader of GISCOME- the Genetics in stroke functional outcome project. This project is part of a program of outcome research that is a collaborative, pan university global partnership of stroke genetics researchers that has produced over 120 publications. The Genetics of Stroke Functional Outcome (GISCOME) network is tri-led by Prof Christina Jern, Prof Arne Lindgren and Prof Jane Maguire. The aim of this network, established in 2012 was to investigate the genetic influences on stroke outcomes, with a focus on functional ability. In phase 1, the GISCOME investigators established the world’s first genome wide association (GWA) genetic dataset for functional outcome of ischemic stroke and reported the first GWAs significant variant for this phenotype. In 2025, Phase-2 is nearing completion and has identified over 20,000 retrospective cases with the aim to meta-analyse and replicate the phase 1 result. This is an ongoing collaboration, and all are welcome to join this group however the GISCOME project is nearing completion and will now be situated in the Global Alliance of Acute and Long Term outcomes.

In addition, Prof Maguire leads a program of research in Genomic Education for Nurses and is a member of the International Society of Nurses in Genetics International Society of Nurses in Genetics (ISONG) - Home and Global Genomics Nurses Alliance Home. She currently supervises three HDR students within this Genomics program.

“Research is something that’s difficult but generating new knowledge creates amazing possibilities and our stroke genetic research is really making a difference,” she said.

Jane has extensive expertise in a range of epidemiological population level designs and other qualitative and quantitative methods, including but not limited to case-control, genome wide association studies, longitudinal studies, mixed-methods, and analytical and descriptive survey development. Jane has experience in biostatistical methods, regression and meta-analysis, narrative, scoping and JBI and Cochrane systematic reviews, and has employed various qualitative designs, including narrative inquiry, ethnography and phenomenological approaches.