A/ProfCharles Cranfield
Associate Head Of School (Teaching And Learning)
Discipline of Molecular Biotechnology
Orcid identifier0000-0003-3608-5440 (opens in a new tab)
- Associate Head Of School (Teaching And Learning)Discipline of Molecular Biotechnology
FUNDED RESEARCH
The UTS Membrane Biophysics Group specialises in novel membrane-based biosensor technologies. We use membrane sensors to test new drugs that are impervious to antimicrobial resistance, to detect biomarkers for cancer, and inflammatory diseases such as inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD). In addition, we delve into the fundamental biophysics of lipid bilayers and cell membranes.
Research Group (Membrane Biophysics Group):
- A/Prof Charles Cranfield (Group Leader)
- Dr Evelyne Deplazes (Honorary, University of Queensland)
- Dr Bruce Cornell (Honorary, SDx Surgical Diagnostics)
- Dr Stephen Holt (Honorary, ANSTO)
- Dr Hedayetul Islam – Research Associate
- Lissy Hartmann (PhD Student)
- Samara Bridge (PhD student)
- Tobias Samuel (Honours)
- Amy Qi Yun Chia (Masters of Philosophy)
- Zongqi Xu (Masters of Philosophy)
- Emily Hellyer (Internship)
- Chun-Hei Ho (Internship)
FUNDED RESEARCH
- GRANTA Label-Free Hybrid Biosensor for Non-Invasive Detection of Early-Stage Bowel Cancer (Samara Bridge)The trustee for Tour De Cure Trust1 Mar 2026 - 31 Dec 2026People funded by this grant:
- Cranfield C,
- Bridge S
- GRANTManufacture of Multiwell Cartridges for High-throughput Screening of Phospholipase Biomarkers in Clinical SamplesCommonwealth Department of Education27 May 2025 - 26 Nov 2026People funded by this grant:
- Cranfield C,
- Bridge S,
- Cornell B,
- Islam MH
- GRANTSamara Bridge - 2024 Scholarship AINSE ANSTO French Embassies (SAAFE) Research Internship ProgramAustralian Institute of Nuclear Science & Engineering1 Oct 2024 - 31 Dec 2025People funded by this grant:
- Cranfield C,
- Donald,
- Bridge S
- GRANTSamara Bridge - Asia Oceania Forum Synchrotron Radiation Research (AOFSRR) SchoolThe Australian Nuclear Science and Technology Organisation11 Aug 2024 - 17 Aug 2024People funded by this grant:
- Cranfield C,
- Bridge S
- GRANTAscertaining the optimal lipid packing parameters and lipid head-group selection for the Phospholipase A2 tethered bilayer lipid membrane sensorThe Australian Nuclear Science and Technology Organisation17 Jul 2024 - 1 Jul 2026People funded by this grant:
- Cranfield C,
- Bridge S,
- Holt S
- GRANTInvestigating the synergy of a Lactoferrin-derived peptide and the anti-fungal drug Amphotericin BThe Australian Nuclear Science and Technology Organisation17 Jul 2024 - 1 Apr 2026People funded by this grant:
- Cranfield C,
- Deplazes E,
- Hartmann L,
- Holt S
- GRANTAscertaining the optimal lipid packing parameters and lipid headgroup selection for the phospholipase A2 tethered bilayer lipid membrane sensorAustralian Institute of Nuclear Science & Engineering1 Jul 2024 - 28 Nov 2026People funded by this grant:
- Cranfield C,
- Bridge S,
- Holt S
- GRANTInvestigating the synergy of a Lactoferrin-derived peptide Lactofungin and the anti-fungal drug Amphotericin BAustralian Institute of Nuclear Science & Engineering1 Jul 2023 - 16 Sep 2026People funded by this grant:
- Cranfield C,
- Deplazes E,
- Hartmann L,
- Holt S
- GRANTTowards a peptide-based adjuvant drug to reduce the toxicity of Amphotericin B in the treatment of invasive fungal infectionsMaridulu Budyari Gumal - The Sydney Partnership for Health, Education, Research and Enterprise (SPHERE)1 Mar 2023 - 31 Dec 2025People funded by this grant:
- Deplazes E,
- Lenardon M,
- Hartmann L,
- Cranfield C
- GRANTMembrane Interaction of Small Molecules Capable of Improving Batten’s Disease Cell PhenotypesTHE AUSTRALIAN CHAPTER OF THE BATTEN DISEASE SUPPORT & RESEARCH ASSOCIATION INCORPORATED1 Jan 2021 - 30 Jun 2022People funded by this grant:
- Cranfield C,
- Clarke R,
- Deplazes E,
- Garcia A
- GRANTCell membrane-disrupting peptides to combat multi-drug resistance in cancer and infectionsUniversity of Technology Sydney31 Jan 2019 - 3 Jun 2021People funded by this grant:
- Deplazes E,
- Cranfield C
- GRANTDetermining the surface coverage and packing of immobilised antimicrobial peptides melimine and melimine-4 and their interactions with model lipid bilayersThe Australian Nuclear Science and Technology Organisation8 Oct 2018 - 10 Oct 2018People funded by this grant:
- Berry T,
- Cranfield C,
- Cornell B,
- Holt S,
- Le Brun A
- GRANTCharacterisation of Tethered Bilayer Lipid Membrane (tBLM) ArchitecturesThe Australian Nuclear Science and Technology Organisation19 Feb 2018 - 21 Feb 2018People funded by this grant:
- Cranfield C,
- Garcia A,
- Berry T,
- Alghalayini A,
- Valenzuela S
- GRANTExamining the Thickness and the Volume Fraction of Tethered Bacterial Model MembranesThe Australian Nuclear Science and Technology Organisation12 Feb 2018 - 15 Feb 2018People funded by this grant:
- Cranfield C,
- Berry T,
- Alghalayini A,
- Valenzuela S,
- Cornell B
- GRANTLipophilic cardiovascular drug disruption of protein/phospholipid membrane interactions.University of Technology Sydney1 Jan 2018 - 19 Mar 2021People funded by this grant:
- Garcia A,
- Cranfield C
- GRANTARC Research Hub for Integrated Device for End-user Analysis at Low-levelsAustralian Research Council27 Mar 2017 - 31 Dec 2023People funded by this grant:
- Valenzuela S,
- Jin D,
- Hilder E,
- Lancaster D,
- Aharonovich I
- GRANTEffect of a Novel Immobilised Antimicrobial Peptide on Bacterial SurfacesAustralian Research Council1 Jan 2016 - 31 Dec 2018People funded by this grant:
- Cranfield C,
- Willcox M,
- Kumar N
- GRANTStructural Changes within the Tethering Elements of tBLMs under the Effect of Bias PotentialsThe Australian Nuclear Science and Technology Organisation1 Sep 2015 - 30 Sep 2015People funded by this grant:
- Cranfield C,
- Valenzuela S,
- Cornell B,
- Le Brun A,
- Holt S
- GRANTStructural Changes within the Tethering Elements of tBLMs under the Effect of Transmembrane PotentialsThe Australian Nuclear Science and Technology Organisation1 Sep 2015 - 31 Dec 2015People funded by this grant:
- Cranfield C,
- Valenzuela S,
- Cornell B,
- Le Brun A,
- Holt S
- GRANTEffects of Bias Potentials on Tethered Lipid BilayersThe Australian Nuclear Science and Technology Organisation16 Feb 2015 - 15 Feb 2016People funded by this grant:
- Cranfield C,
- Valenzuela S,
- Holt S,
- Cornell B,
- Le Brun A
- GRANTNational Health and Medical Research Council1 Jan 2013 - 31 Dec 2015People funded by this grant:
- Martinac B,
- Corry B,
- Cranfield C
